Is epilepsy a mental illness? No, it’s not. But it can put people at greater risk of mood disorders such as bipolar disorder. We are increasingly discovering that mood disorders and epilepsy coexist. But there is still much that we do not understand in the connection between them.
According to Centers for Disease Control and Prevention, about 30 percent of people with epilepsy also suffer from serious mental illness, including bipolar disorder, major depression, and schizophrenia. The prevalence of depression has been shown to be much higher than that of bipolar disorder.
Link between epilepsy and bipolar disorder
Rafael Forest, a neuropsychologist at the Marcus Institute of Neurology, says there is likely a correlation between bipolar disorder and epilepsy. Bipolar disorder is characterized by bouts of depression, but also mania “highs” when a person can move away from reality. They may have a reduced need for rest or sleep, as well as lack of appetite, lack of concentration, racing thoughts, shortsightedness, and feelings of selfishness or empowerment.
Wald says structural differences in the brain are similar between people with mood disorders, including bipolar disorder, and people with mood disorders. epilepsy. “Both diseases are associated with known chemical and structural differences in the brain. [that are different] from people who don’t have seizures or mood disorders,” Wald says.
The chronic nature of the disease and the hopelessness that accompanies it play a role, but that’s not all. The relationship between bipolar disorder and epilepsy is complex.
Epilepsy and seizures
According to Epilepsy Foundationthose who have seizures are also affected by other neurobiological factors such as head injuries, strokes associated with the onset of certain types of epilepsy, and neurotransmitter problems in the brain associated with both epilepsy and bipolar disorder.
In addition, medications such as phenobarbital have also been shown to cause depression in some people. There are also some indications that an excess of cytokines (a protein associated with the immune response) in the brain may be present in patients with epilepsy and bipolar disorder. Dysfunction in the temporal lobe, the part of the brain that processes auditory functions and codes for memories, may also play a role in both diseases.
Treatment of epilepsy with bipolar disorder
It is also important to note that according to a 2013 study published in the journal epileptic behaviorthat there would be a genetic component to both diseases. Bipolar disorder is associated with a family history, as are some types of epilepsy. According to the study, “it is critical to conduct a study of the patient’s personal history and family psychiatric history in order to minimize the risk of potential psychiatric symptoms.”
According to a 2016 study published in the journal FocusThe researchers found that both conditions respond to similar medications, which may indicate similar pathologies in the brain. “In some cases, the symptoms of bipolar disorder and epilepsy can be treated simultaneously with the same anticonvulsant,” the study authors write. For example, the anticonvulsant drug levetiracetam has been shown to treat both disorders.
Signs of Bipolar Disorder in Patients with Epilepsy
Patients with epilepsy have a one in three chance of also having a mood disorder, Wald says. If the patient has bipolar disorder, look for signs of mania, he says. “Mania includes less need for sleep, increased focus, risk-taking behavior, excessive spending, and other such symptoms,” he says.
Bipolar disorder, like epilepsy, requires treatment. It’s not something you can live with because it’s a chemical imbalance that needs proper treatment. But some treatments have been shown to be effective and allow patients with both diseases to live normal lives.
Read more: What is epilepsy and what should we know about it?